Endrin
Endrin is an insecticide that was commonplace among cotton growers and for the treament of cereals. It was also used to kill rodents. It is a neurotoxin. It is …
| Names | |
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| IUPAC name
(1R,2S,3R,6S,7R,8S,9S,11R)-3,4,5,6,13,13-Hexachloro-10-oxapentacyclo[6.3.1.13,6.02,7.09,11]tridec-4-ene
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| Other names
Mendrin, Compound 269, (1aR,2S,2aS,3S,6R,6aR,7R,7aS)-3,4,5,6,9,9-hexachloro-1a,2,2a,3,6,6a,7,7a-octahydro-2,7:3,6-dimethanonaphtho[2,3-b]oxirene, 1,2,3,4,10,10-Hexachloro-6,7-epoxy-1,4,4a,5,6,7,8,8a-octahydro-1,4-endo,endo-5,8-dimethanonaphthalene
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| Identifiers | |
3D model (JSmol)
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| ChEBI | |
| ChEMBL | |
| ChemSpider | |
| ECHA InfoCard | 100.000.705 |
| EC Number |
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| KEGG | |
PubChem CID
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| RTECS number |
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| UNII | |
| UN number | 2761 |
CompTox Dashboard (EPA)
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| Properties | |
| C12H8Cl6O | |
| Molar mass | 380.907 g/mol |
| Appearance | Colorless to tan crystalline solid |
| Density | 1.77 g/cm3 [1] |
| Melting point | 200 °C (392 °F; 473 K) (decomposes) |
| 0.23 mg/L[2] | |
| Vapor pressure | 2.6 x 10-5 Pa[1] |
| Hazards | |
| GHS labelling: | |
| Danger | |
| H301, H310, H351, H372, H410 | |
| P201, P202, P260, P262, P264, P270, P273, P280, P281, P301+P310, P302+P350, P308+P313, P310, P314, P321, P322, P330, P361, P363, P391, P405, P501 | |
| NFPA 704 (fire diamond) | |
| Flash point | noncombustible [3] |
| Lethal dose or concentration (LD, LC): | |
LD50 (median dose)
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3 mg/kg (oral, monkey) 16 mg/kg (oral, guinea pig) 10 mg/kg (oral, hamster) 3 mg/kg (oral, rat) 7 mg/kg (oral, rabbit) 1.4 mg/kg (oral, mouse)[4] |
LDLo (lowest published)
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5 mg/kg (cat, oral)[4] |
| NIOSH (US health exposure limits): | |
PEL (Permissible)
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TWA 0.1 mg/m3 [skin][3] |
REL (Recommended)
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TWA 0.1 mg/m3 [skin][3] |
IDLH (Immediate danger)
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2 mg/m3[3] |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Endrin is an insecticide that was commonplace among cotton growers and for the treament of cereals. It was also used to kill rodents. It is a neurotoxin. It is a stereoisomer of Dieldrin. In the soil, it can take up to twelve years to decay. It is one of the twelve substances listed in the Stockholm Convention on Persistent Organic Pollutants, and its production, trade and use is banned since 2004.
References
- ↑ 1.0 1.1 "Endrin". Deutsche Gesellschaft für Technische Zusammenarbeit. Retrieved 13 March 2015.
- ↑ "Endrin (PDS)". IPCS. Archived from the original on 2 July 2014. Retrieved 13 March 2015.
- ↑ 3.0 3.1 3.2 3.3 NIOSH Pocket Guide to Chemical Hazards. "#0252". National Institute for Occupational Safety and Health (NIOSH).
- ↑ 4.0 4.1 "Endrin". Immediately Dangerous to Life or Health Concentrations (IDLH). National Institute for Occupational Safety and Health (NIOSH). 4 December 2014. Retrieved 19 March 2015.
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