RSPO2
• heparin binding• signaling receptor binding• GO:0001948، GO:0016582 ربط بروتيني• GO:0005110 frizzled binding
RSPO2 (R-spondin 2) هوَ بروتين يُشَفر بواسطة جين RSPO2 في الإنسان.[1][2][3][4][5]
الوظيفة
هذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018) |
الأهمية السريرية
هذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018) |
المراجع
- ^ Cadieu E، Neff MW، Quignon P، Walsh K، Chase K، Parker HG، Vonholdt BM، Rhue A، Boyko A، Byers A، Wong A، Mosher DS، Elkahloun AG، Spady TC، André C، Lark KG، Cargill M، Bustamante CD، Wayne RK، Ostrander EA (أكتوبر 2009). "Coat variation in the domestic dog is governed by variants in three genes". Science. ج. 326 ع. 5949: 150–3. DOI:10.1126/science.1177808. PMC:2897713. PMID:19713490.
- ^ Jin YR، Turcotte TJ، Crocker AL، Han XH، Yoon JK (2011). "The canonical Wnt signaling activator, R-spondin2, regulates craniofacial patterning and morphogenesis within the branchial arch through ectodermal–mesenchymal interaction". Developmental Biology. ج. 352 ع. 1: 1–13. DOI:10.1016/j.ydbio.2011.01.004. PMC:3089906. PMID:21237142.
- ^ "Entrez Gene: R-spondin 2". مؤرشف من الأصل في 2010-12-05.
- ^ Kazanskaya O، Glinka A، del Barco Barrantes I، Stannek P، Niehrs C، Wu W (أكتوبر 2004). "R-Spondin2 is a secreted activator of Wnt/beta-catenin signaling and is required for Xenopus myogenesis". Dev. Cell. ج. 7 ع. 4: 525–34. DOI:10.1016/j.devcel.2004.07.019. PMID:15469841.
- ^ Kim KA، Zhao J، Andarmani S، Kakitani M، Oshima T، Binnerts ME، Abo A، Tomizuka K، Funk WD (يناير 2006). "R-Spondin proteins: a novel link to beta-catenin activation". Cell Cycle. ج. 5 ع. 1: 23–6. DOI:10.4161/cc.5.1.2305. PMID:16357527.
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